A potential therapeutic target miR-26b in tongue squamous cell carcinoma
نویسندگان
چکیده
منابع مشابه
Tongue Squamous Cell Carcinoma: A Clinical Study
Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. Although the level of healthcare has significantly improved, the survival rate is still low with an...
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The aim of the present study was to identify agents capable of inhibiting the invasion and metastasis of tongue squamous cell carcinoma and thereby improve the outcomes of patients suffering from tongue cancer. FRMD4A antibodies were used to probe 78 paraffin-embedded specimens of tongue squamous cell carcinoma and 15 normal tongue tissues, which served as controls. Immunohistochemical methods ...
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BACKGROUND & AIMS Cyclooxygenase-2 (COX-2) is known to promote the carcinogenesis of esophageal squamous cell carcinoma (ESCC). There are no reports on whether microRNAs (miRNAs) regulate COX-2 expression in ESCC. This study investigated the effect of miR-101 on ESCC through modulating COX-2 expression in ESCC. METHODS Real-time quantitative reverse transcription-polymerase chain reaction (RT...
متن کاملTongue squamous cell carcinoma in a patient with systemic sclerosis: A case report
Objective: Systemic sclerosis (SS) is a chronic autoimmune disease of connective tissue, which involves skin and internal organs, and results in collagen deposition and fibroblasts activation. Studies have reported a higher risk of malignancy in patients with progressive systemic sclerosis (PSS).The aim of this study is to report a case of tongue squamous cell carcinoma (SCC) in a patient with ...
متن کاملtongue squamous cell carcinoma: a clinical study
background and objectives: squamous cell carcinoma of the tongue (sccot) is the most common malignant neoplasm in oral cavity. at the time of the diagnosis of sccot regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. although the level of healthcare has significantly improved, the survival rate is still low with an un...
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ژورنال
عنوان ژورنال: Otorhinolaryngology-head and neck surgery
سال: 2021
ISSN: ['2398-4937']
DOI: https://doi.org/10.15761/ohns.1000259